Walker-Warburg Syndrome Overview What is Walker-Warburg syndrome? Walker-Warburg syndrome is a genetic condition that affects the muscles in your child’s body, including their brain and their eyes. This condition is a type of congenital muscular dystrophy present at birth or infancy that leads to progressive muscle weakness over time. This condition causes life-threatening symptoms for children and a shortened life expectancy. What is dystroglycanopathy? You might hear Walker-Warburg syndrome identified as dystroglycanopathy. Walker-Warburg syndrome is a form of congenital (appears at birth) muscular dystrophy, which is a group of conditions that target the muscles of your child’s body. There are several types of muscular dystrophy categorized as dystroglycanopathy, which identifies forms of muscular dystrophy caused by genes that produce the dystroglycan protein. Walker-Warburg syndrome is the most severe type of dystroglycanopathy. How common is Walker-Warburg syndrome? Walker-Warbur...