Health and Fitness

Crohn's disease Overview Crohn's disease is a type of inflammatory bowel disease (IBD) that causes swelling and irritation of the tissues, called inflammation, in the digestive tract. This can lead to belly pain, severe diarrhea, fatigue, weight loss and malnutrition. Inflammation caused by Crohn's disease can affect different areas of the digestive tract in different people. Crohn's most commonly affects the end of the small intestine and the beginning of the large intestine. The inflammation often spreads into the deeper layers of the bowel. Crohn's disease can be both painful and debilitating. Sometimes, it may lead to serious or life-threatening complications. There's no known cure for Crohn's disease, but therapies can greatly reduce its symptoms and even bring about long-term remission and healing of inflammation. With treatment, many people with Crohn's disease can function well. Symptoms Symptoms of Crohn's disease typically include: Diarrhea...

Motion Sickness Overview What is motion sickness? Motion sickness is a condition that happens when your eyes, inner ear and body send conflicting messages to your brain. You can develop the condition whenever your body is staying still but you’re being moved by a vehicle, like when you’re riding in a car or standing on a boat deck. Some people get a kind of motion sickness while playing video games and virtual reality games (virtual motion sickness or VMS). Symptoms include nausea, breaking out in cold sweat or headache. Fortunately, there are ways to prevent motion sickness or ease its symptoms. Symptoms Motion sickness symptoms can develop slowly or appear all at once. Common symptoms include: Dizziness. Fatigue. Headache. Feeling irritable. Nausea and vomiting. Rapid breathing or feeling like you need to take gulps of air. Salivating more than usual. Sweating, particularly a cold sweat. Causes Motion sickness happens when your brain gets conflicting messages from the parts of your b...

Helicobacter pylori (H. pylori) infection Overview A Helicobacter pylori infection is a common stomach infection. It's caused by a germ called Helicobacter pylori, a bacteria also known as H. pylori. More than half the people in the world may have an H. pylori infection at some point in their lives. These infections often happen during childhood, especially in developing countries. H. pylori germs seem to spread through contact with an infected person's bodily fluids, including vomit, stool or saliva. This includes contact that happens through poor hand hygiene. The germs also can spread through tainted food and water. H. pylori infections can cause stomach pain, bloating, gas and other symptoms. But most people who become infected don't have symptoms. Sometimes, H. pylori infections lead to sores called peptic ulcers in the lining of the stomach or small intestine. Much less often, these infections can lead to stomach cancer. Your healthcare professional likely will test y...

Tietze Syndrome Overview Tietze syndrome (Tietze’s disease) is a rare inflammatory condition that affects the cartilage in your rib cage. It causes musculoskeletal chest pain and swelling at the front and top part of your chest wall. Your upper ribs (the first 10) have cartilage tips (costal cartilage) where they connect to your sternum (breastbone). The joints where these tips connect (costochondral joints) also have cartilage in them. General inflammation of the cartilage in your rib cage is called costochondritis. But Tietze syndrome is more specific. It typically affects just one of your top four ribs. It’s also distinctive for causing noticeable swelling. Healthcare providers aren’t sure what causes Tietze syndrome (also called costochondral junction syndrome). But it doesn’t seem to be serious. You can treat it at home with rest and pain relievers. Symptoms What are Tietze syndrome symptoms? The most obvious way Tietze syndrome will affect you is by the pain in your chest, which ...

Otulipenia Overview Otulipenia is an extremely rare autoinflammatory disease caused by mutations in the OTULIN gene. The resulting protein deficiency leads to uncontrolled systemic inflammation and severe tissue damage. Symptoms typically emerge in the first weeks of life and include recurring fevers, painful swollen joints, skin rashes, diarrhea, and failure to thrive. Symptoms Recurring Fevers: Unexplained, episodic fevers that are not caused by typical infections. Skin Rashes: Red, inflammatory rashes which often present as painful nodules or bumps due to inflammation in the fatty tissue beneath the skin (panniculitis). Joint and Muscle Pain: Swollen, painful joints (arthritis/arthralgia) and muscle pain (myalgia). Gastrointestinal Issues: Chronic diarrhea, abdominal pain, and overall intestinal inflammation. Failure to Thrive: Infants severely struggle to grow and gain weight at a normal, healthy rate. Lipodystrophy : An abnormal distribution or loss of fatty tissue in the body...

Aicardi-Goutières syndrome (AGS)  Overview Aicardi-Goutières syndrome (AGS) is a rare, inherited autoimmune and neurological disorder. It primarily affects the brain, immune system, and skin by causing the body to overproduce a chemical messenger called interferon. This triggers the immune system to attack the brain’s white matter, resulting in permanent damage. Symptoms Early-Onset (Congenital) AGS Infants with early-onset AGS present at birth, often mimicking a congenital infection.Brain, liver, and spleen inflammation Low platelet counts and bleeding issues (thrombocytopenia)Slower head growth leading to microcephaly (smaller head size)Seizures and trouble feeding Rapid, involuntary twitching of the face and limbs Later-Onset AGS Most infants with AGS develop normally for their first few weeks or months of life before showing rapid neurological and physical regression. Neurological & Motor: Extreme irritability, inconsolable crying, weak or stiffened muscles (spasticity), an...